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Editas Medicine Associate Scientist I, Analytical Development - 2472 in Cambridge, Massachusetts

At Editas, we’re driven by a collective purpose, to bring transformative and life changing therapies to people living with serious diseases with the greatest unmet needs. This fuels our drive to excel in scientific innovation, allowing us to harness the power and potential of CRISPR/Cas9 and CRISPR/Cpf1 (Cas12a) gene editing.

We believe our people are at the core of everything we do, and we’re committed to cultivating a culture where every individual feels valued and included. To do this, we strive to integrate belonging, inclusivity, diversity, and equity into every aspect of our organization.

Together, we are leading the way towards a healthier and more equitable future.

Position Summary

Editas is seeking an Associate Scientist to join our Analytical Development group. This person will work closely with teams across research & development to execute various biophysical methods for gene editing components and drug product characterization. Ideal candidates will have demonstrated experience with assay development, tech transfer of assays to QC, and the ability to work collaboratively across cross-functional teams. Proficient and experienced in Mass Spectrometry and HPLC method development highly preferred.

As the Associate Scientist in Analytical Development, you will be responsible for:

  • Development and execution of various biophysical methods to gene-editing components and drug product characterization, release, and stability.

  • Identification of protein PTMs, analysis by native mass spectrometry and optimization of in process sample prep. Support routine sample prep for process characterization, comparability and PPQ samples.

  • Independent data interpretation and analysis, organize data and work with bioinformatics and other groups to simplify or update data workflows

  • Routine mass spectrometry and lab equipment maintenance

  • Opportunity to spearhead one or multiple assay development projects.

  • Cross-train personnel on assays, as required.

  • Meticulous documentation in electronic lab notebook (ELN).

  • Compile and present data in various meetings.

  • Assist in authoring and reviewing of test methods, technical reports, and supporting procedures.

Requirements

Required Qualifications:

The ideal candidate will possess:

  • B.S. in chemistry, biotechnology, biomedical engineering, or related field with 5+ years of relevant experience

  • M.S. in chemistry, biotechnology, biomedical engineering, or related field with 3+ years of relevant experience

  • Experience and/or familiarity with HPLC/UHPLC assay development is required. Experience and/or familiarity with sample preparation for mass spectrometry and data analysis is required.

  • Experience with protein or peptide analytical techniques.

  • Experience with reagent and sample preparation, equipment maintenance, troubleshooting.

Preferred Qualifications:

Additionally, candidates with the following attributes are preferred:

  • Collaborative attitude within team and across functions

  • Strong organizational skills with the ability to multi-task, problem-solve, prioritize assignments, and adjust priorities to meet goals.

Benefits

Benefits Summary:

Editas provides a comprehensive array of benefits to all employees, including a Blue Cross Blue Shield PPO Medical Plan, a company-funded Health Savings Account, Dental and Vision Insurance, Life and Disability Insurance, Dependent Care Account, Tuition Reimbursement, 401(k) plan with company match, Employee Stock Purchase Plan, Employee Assistance Plan, Wellness Programs, and a flexible Paid Time Off policy.

If you are a results-focused and collaborative professional with a passion for advancing transformative therapies, we invite you to apply. Join us at the forefront of genetic innovation and be a key contributor to Editas Medicine's mission of redefining healthcare through cutting-edge genetic technologies.

Fostering Belonging. Fueling Innovation. Transforming Lives.

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